Concepedia
Journal of Molecular Biology · 2003 · 30 citations · 13 references
Life SciencesBiochemistryMolecular BiologyBiophysical ChemistryEnzymologyMolecular BiophysicsBiomolecular ThermodynamicsDna StructureMacromolecular AssemblyThermostable EnzymesThermophilic MicroorganismsTopoisomerase Activity
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Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break
Leroy F. Liu, Chen Liu, Bruce Alberts · Cell · 1980 · 546 citations
Life Sciences, Biochemistry, Molecular Biology +14
Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications.
James R. Brown, W. Ford Doolittle · Proceedings of the National Academy of Sciences · 1995 · 381 citations
Life Sciences, Biology, Evolutionary Biology +17
A Sign Inversion Mechanism for Enzymatic Supercoiling of DNA
Patrick O. Brown, Nicholas R. Cozzarelli · Science · 1979 · 329 citations
Life Sciences, Biochemistry, Molecular Biology +8
Roles of Topoisomerases in Maintaining Steady-state DNA Supercoiling in Escherichia coli
Lynn Zechiedrich, Arkady Khodursky, Sophie Bachellier‐Bassi et al. · Journal of Biological Chemistry · 2000 · 327 citations · Full text
Life Sciences, Microbiology, Molecular Biology +10
DNA gyrase action involves the introduction of transient double-strand breaks into DNA.
Kiyoshi Mizuuchi, L. Mark Fisher, M H O'Dea et al. · Proceedings of the National Academy of Sciences · 1980 · 241 citations · Full text