Concepedia

Decreased expression of B7 costimulatory molecules and major histocompatibility complex class‐I in human hepatocellular carcinoma

Keishi Fujiwara, Toshihiro Higashi, Kazuhiro Nouso, Harushige Nakatsukasa, Yoshiyuki Kobayashi, Masayuki Uemura, Shinichiro Nakamura, Shuichiro Sato, Tadashi Hanafusa, Yasuhiro Yumoto,

Journal of Gastroenterology and Hepatology · 2004 · 58 citations · 36 references

DOI

Abstract

These findings suggest the potential role of B7 co-stimulatory molecules and HLA class-I molecules in facilitating HCC escape from immune surveillance without the involvement of IL-10.

References

36

Terminology of nodular hepatocellular lesions

Ian R. Wanless · Hepatology · 1995 · 1.1K citations · Full text

Hepatology, Nodular Hepatocellular Lesions, Histopathology +8

CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

Lewis L. Lanier, S O'Fallon, Chamorro Somoza et al. · The Journal of Immunology · 1995 · 487 citations

Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration

Yoshito Wada, Osamu Nakashima, Rumiko Kutami et al. · Hepatology · 1998 · 396 citations · Full text

B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.

Christophe Caux, Béatrice Vanbervliet, Catherine Massacrier et al. · The Journal of Experimental Medicine · 1994 · 346 citations · Full text

Adaptive Immune System, Immunology, Immunologic Mechanism +17

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generatedin vitro from CD34+ hematopoietic progenitor cells

Andréas Mackensen, Birgit Herbst, Ji-Li Chen et al. · International Journal of Cancer · 2000 · 335 citations · Full text