Outcome of the p53-mediated DNA damage response in neuroblastoma is determined by morphological subtype and MYCN expression

Jane Carr‐Wilkinson, Rebecca E. Griffiths, Rebecca Elston, Laura D. Gamble, Bojidar Goranov, Christopher P.F. Redfern, John Lunec, Deborah A. Tweddle

Cell Cycle · 2011 · 15 citations · 0 references

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Abstract

The downstream response to DNA damage in p53 wild-type neuroblastoma cell lines is p53 dependent, and determined both by the morphological sub-type and MYCN expression.