Bone: Formation by Autoinduction

Marshall R. Urist

Science

MechanobiologyRegenerative MedicineInductor CellsDevelopmental BiologyBone Biology +12

Novel Regulators of Bone Formation: Molecular Clones and Activities

John M. Wozney, Vicki Rosen, Anthony Celeste, +5

Science

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

M Kozak

Journal of Biological Chemistry

Molecular BiologyProtein SynthesisTranscriptional RegulationTranslational BiologyGene Structure +15

Regulation of Cell Survival by Secreted Proneurotrophins

Ramee Lee, Pouneh Kermani, Kenneth K. Teng, +1

Science

Recombinant human bone morphogenetic protein induces bone formation.

Elizabeth A. Wang, Vicki Rosen, Josephine D’Alessandro, +7

Proceedings of the National Academy of Sciences

Regenerative MedicineRecombinant Human Bmp-2aSingle BmpDevelopmental BiologyBone Biology +12

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

Hongbing Zhang, Allan Bradley

Development

A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

Jeff S. Mumm, Eric H. Schroeter, Meera Saxena, +5

Molecular Cell

Protein FunctionSignal TransductionSignaling PathwayMolecular RegulationNatural Sciences +8

Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor.

B. Bugler, F. Amalric, Hervé Prats

Molecular and Cellular Biology

Developmental BiologyTranslation DeterminesCell SignalingAug Start CodonsSubcellular Localization +10

Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells

Sylvie Gallea, François Lallemand, Azeddine Atfi, +8

Bone

SclerostinDevelopmental BiologySignal TransductionBone Morphogenic ProteinCell Signaling +6

Regulation of Bone Morphogenetic Protein Activity by Pro Domains and Proprotein Convertases

Daniel B. Constam, Elizabeth J. Robertson

The Journal of Cell Biology

Pro DomainsProprotein ConvertasesSclerostinDevelopmental BiologyProtein Function +13