Concepedia

Inhibition of T-Cell Activation by Retinal Pigment Epithelial Cells Derived From Induced Pluripotent Stem Cells

Sunao Sugita, Hiroyuki Kamao, Y. Iwasaki, Satoshi Okamoto, Tomoyo Hashiguchi, Kyoko Iseki, Naoko Hayashi, Michiko Mandai, Masayo Takahashi

Investigative Ophthalmology & Visual Science · 2015 · 69 citations · 25 references

DOI

Abstract

Cultured iPS-derived retinal cells fully suppress T-cell activation. Transplantation of iPS-RPE cells into the eye might be a therapy for retinal disorders.

References

25

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

Junying Yu, Kejin Hu, Kim Smuga-Otto et al. · Science · 2009 · 2.3K citations · Full text

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A more efficient method to generate integration-free human iPS cells

Keisuke Okita, Yasuko Matsumura, Yoshiko Sato et al. · Nature Methods · 2011 · 2K citations

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Immunogenicity of induced pluripotent stem cells

Tongbiao Zhao, Zhen‐Ning Zhang, Zhili Rong et al. · Nature · 2011 · 1.4K citations

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Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells

Ryoko Araki, Masahiro Uda, Yuko Hoki et al. · Nature · 2013 · 496 citations

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Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.

Scott W. Cousins, Mead M. McCabe, David Danielpour et al. · PubMed · 1991 · 477 citations

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