M cells and transmural heterogeneity of action potential configuration in myocytes from the left ventricular wall of the pig heart

Abstract

In young adult pigs, M cells can be identified by a steep frequency response of the APD and by a spike-and-dome configuration. These cells are mostly, but not exclusively, found in the midmyocardium, and could contribute to the ECG characteristics. Their properties may however be different from those of other species, including humans.