Characterizing interspecies uncertainty using data from studies of anti-neoplastic agents in animals and humans

Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.

Emil J. Freireich, E. A. Gehan, David P. Rall et al. · PubMed · 1966 · 1.4K citations

Comparative Toxicology, Quantitative Comparison, Medicine +10

Integrated risk information system (IRIS)

Linda C. Tuxen · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) · 1990 · 1.2K citations · Full text

Design and Analysis of Phase I Clinical Trials

Barry E. Storer · Biometrics · 1989 · 918 citations

Clinical Endpoint, Optimal Experimental Design, New Drug +16

Reference dose (RfD): Description and use in health risk assessments

Donald Grove Barnes, Michael L. Dourson · Regulatory Toxicology and Pharmacology · 1988 · 816 citations

Radiation Testing, Patient Safety, Health Risk Assessment +6

Regulatory history and experimental support of uncertainty (safety) factors

Michael L. Dourson, Jerry F. Stara · Regulatory Toxicology and Pharmacology · 1983 · 424 citations

High Uncertainty, Engineering, Uncertainty Quantification +7