Searching for Peptide Ligands with an Epitope Library

Jamie K. Scott, George P. Smith

Science

Epitope LibraryProtein FoldingMedicineNatural SciencesBacteriophage +13

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

Ursula Klingmüller, Ulrike Lorenz, Lewis C. Cantley, +2

Cell

Signal TransductionSignaling PathwaySpecific RecruitmentReceptor Tyrosine KinaseApoptosis +10

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

L. D. Shultz, Peter A. Schweitzer, T. V. Rajan, +5

Cell

BiologyMurine Motheaten LocusGeneticsMolecular GeneticsMedicine +2

A Novel Rab5 GDP/GTP Exchange Factor Complexed to Rabaptin-5 Links Nucleotide Exchange to Effector Recruitment and Function

Hisanori Horiuchi, Roger Lippé, Heidi M. McBride, +8

Cell

Protein FunctionSignal TransductionG Protein-coupled ReceptorMolecular BiologyBiochemical Interaction +5

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

Hing Wo Tsui, Katherine A. Siminovitch, Loretta de Souza, +1

Nature Genetics

BiologyGeneticsViable Motheaten MiceGenetic MechanismMolecular Genetics +2

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

Shi‐Hsiang Shen, Lison Bastien, Barry I. Posner, +1

Nature

Protein FunctionSignal TransductionSignaling PathwayBiochemistryNatural Sciences +9

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.

R. James Matthews, David B. Bowne, Elsa R. Flores, +1

Molecular and Cellular Biology

Molecular RegulationMolecular BiologySh2 DomainSignaling PathwayReceptor Tyrosine Kinase +17

Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13.

T Yi, John L. Cleveland, James N. Ihle

Molecular and Cellular Biology

GeneticsMolecular BiologyHematopoietic Cell PhosphataseSh2 DomainsHuman Chromosome 12P12-p13 +15

Hematopoietic Cell Phosphatase Associates with the Interleukin-3 (IL-3) Receptor β Chain and Down-Regulates IL-3-Induced Tyrosine Phosphorylation and Mitogenesis

Taolin Yi, Alice Mui, Gerald Krystal, +1

Molecular and Cellular Biology

InflammationCytokineSignal TransductionImmune Cell DevelopmentMedicine +12

Isolation of a src homology 2-containing tyrosine phosphatase.

Jorge Plutzky, Benjamin G. Neel, Robert Rosenberg

Proceedings of the National Academy of Sciences

Protein FunctionSignal TransductionSignaling PathwayBiochemistryNatural Sciences +9