Free radical spin trap α-phenyl-N-tert-butyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury

Mitochondrial control of nuclear apoptosis.

Naoufal Zamzami, Santos A. Susín, Philippe Marchetti et al. · The Journal of Experimental Medicine · 1996 · 1.4K citations · Full text

Mitophagy, Apoptosis, Mitochondrial Permeability Transition +16

Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia

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Cellular Localization, Apoptosis, Cell Death +25

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

M Crompton, H Ellinger, A Costi · PubMed · 1988 · 847 citations · Full text

Cardiac Muscle, Cyclosporin A, Redox Biology +18

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model

Maj‐Lis Smith, George Bendek, Nils Dahlgren et al. · Acta Neurologica Scandinavica · 1984 · 736 citations

Cerebral Vascular Regulation, Neurovascular Disease, Long-term Recovery +23

Induction of Caspase-3-Like Protease May Mediate Delayed Neuronal Death in the Hippocampus after Transient Cerebral Ischemia

Jun Chen, Tetsuya Nagayama, Kunlin Jin et al. · Journal of Neuroscience · 1998 · 704 citations · Full text