Revista Brasileira de Engenharia Biomédica · 2013 · 10 citations · 5 references
Life SciencesPhysiologyBiological Systems ModelingBiomechanicsPhysiological Systems ModelingBiomechanical ModelingGastrointestinal PhysiologyGastrointestinal System ModelingHemodynamics ModelingGastrointestinal Motility ModelingPhysiologically Based Gastrointestinal ModelingSatiety MechanismsSatiety ResponseSatiety ResponsivenessSystem Response AnalysisUpper Esophageal Sphincter Physiology
INTRODUCTION: This paper shows a proposal for the mathematical modeling of the human esophagus using Bond Graph formalism and the interference in the satiation of an individual by way of an Esophageal Flow Controller (EFC). Therefore, it was evaluated that there is a significant change in fall time that affects the process of human satiety when the diameter of the esophagus is reduced. METHODS: As a first study, the analysis did not consider all hypothetical influences; only the most important variables were considered. RESULTS: As a result, the order of the final equation was x ∈ ℜ10. Furthermore, the designed model can be classified as linear, established and time invariant. CONCLUSION: The simulation results allow us to conclude that using the EFC in order to reduce the esophageal diameter in the upper esophageal sphincter area of 3cm by 1 cm implies that the system response will be slower; and consequently this reduction will interfere with satiety.
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Textbook of Medical Physiology
Annals of Internal Medicine · 1966 · 9.8K citations
Life Sciences, Anatomy, Physiology +12
TEXTBOOK OF MEDICAL PHYSIOLOGY
Arthur C. Guyton · The American Journal of the Medical Sciences · 1967 · 2.9K citations
Life Sciences, Anatomy, Physiology +12
Roberto Oliveira Dantas, Leda Maria Tavares Alves, Weslania Viviane Nascimento · Diseases of the Esophagus · 2010 · 12 citations · Full text