Concepedia

Angiotensin II and epidermal growth factor receptor cross‐talk mediated by a disintegrin and metalloprotease accelerates tumor cell proliferation of hepatocellular carcinoma cell lines

Hidenori Itabashi, Chihaya Maesawa, Hiroki Oikawa, Koji Kotani, Eiichi Sakurai, Kuniyuki Kato, Hideaki Komatsu, Hiroyuki Nitta, Hidenobu Kawamura, Go Wakabayashi,

Hepatology Research · 2008 · 43 citations · 45 references

Abstract

These results suggest that AngII-EGFR cross-talk signaling mediated by ADAMs is involved in the proliferation and invasion activities of several HCC cell lines.

References

45

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

Inflammation, Molecular Pharmacology, Liver Fibrosis +13

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

Henrik Daub, Christian Wallasch, Axel Ullrich · Nature · 1996 · 1.5K citations

Signal Transduction, Developmental Biology, Molecular Physiology +10

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

Masanori Asakura, Masafumi Kitakaze, Seiji Takashima et al. · Nature Medicine · 2002 · 718 citations

Adam12 Processing, Cardiac Muscle, Cardiomyopathy +9

Pooled Analysis of Prognostic Impact of Urokinase-Type Plasminogen Activator and Its Inhibitor PAI-1 in 8377 Breast Cancer Patients

Maxime P. Look, Wim L.J. van Putten, Michael J. Duffy et al. · JNCI Journal of the National Cancer Institute · 2002 · 600 citations · Full text

Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?

Anthony F. Lever, David Hole, C. Gillis et al. · The Lancet · 1998 · 545 citations

Inhibitory Activity, Oncology, Medicine +8