Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic KATP channel

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Data Reduction and Error Analysis for the Physical Sciences.

E. L. C., P. R. Bevington · Journal of the American Statistical Association · 1972 · 3.6K citations

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Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

Lydia Aguilar‐Bryan, Colin G. Nichols, Sérgio Wechsler et al. · Science · 1995 · 1.3K citations

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

Stephen J. Tucker, Fiona M. Gribble, Chao Zhao et al. · Nature · 1997 · 764 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +15

Association and Stoichiometry of KATP Channel Subunits

John P. Clement, Kumud Kunjilwar, Gabriela González et al. · Neuron · 1997 · 704 citations · Full text

Channelopathies, Signal Transduction, Molecular Physiology +8