Effect of ara-C incorporation on deoxyribonucleic acid synthesis in cells

Correlation of cytotoxicity with incorporation of ara-C into DNA.

Donald Küfe, Pierre Major, E.Michael Egan et al. · Journal of Biological Chemistry · 1980 · 362 citations · Full text

Dna Damage, Immunology, Cell Death +17

Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5'-triphosphate.

Frank L. Graham, G. F. Whitmore · PubMed · 1970 · 286 citations

Dna Analysis, Molecular Biology, Ara-c Incorporation +16

Effects of Hydroxyurea and 1‐β‐D‐Arabinofuranosyl‐cytosine on Deoxyribonucleotide Pools in Mouse Embryo Cells

Lambert Skoog, Bo Nordenskjöld · European Journal of Biochemistry · 1971 · 278 citations · Full text

Dgtp Pool, Molecular Biology, Cell Culture +20

Dose schedule and antitumor studies of arabinosyl cytosine (NSC 63878).

Emil Frei, John N. Bickers, James S. Hewlett et al. · PubMed · 1969 · 215 citations

Bone Marrow Function, Immunology, Pharmacotherapy +18

Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.

Peter G.W. Plagemann, Richard März, Robert M. Wohlhueter · PubMed · 1978 · 191 citations

Cellular Physiology, Biosynthesis, Membrane Transport +18