Neuroprotection by Orexin-A via HIF-1α induction in a cellular model of Parkinson's disease

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text

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Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

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Hypoxia-inducible Factor Prolyl 4-Hydroxylase Inhibition

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Hypocretin (orexin) loss in Alzheimer's disease

Rolf Fronczek, Sarita van Geest, Marijke Frölich et al. · Neurobiology of Aging · 2011 · 244 citations

Alzheimer's Disease, Dementia, Neurology +4