Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Federica Sallusto, Danielle Lenig, Reinhold Förster, +2

Nature

Autoimmune DiseaseAdaptive Immune SystemImmunologyMemory TImmunodominance +9

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

David Masopust, Vaiva Vezys, Amanda L. Marzo, +1

Science

ImmunologyPreferential LocalizationLytic ActivityAntigen ProcessingT Cells +19

Lineage relationship and protective immunity of memory CD8 T cell subsets

E. John Wherry, Volker Teichgräber, Todd C. Becker, +5

Nature Immunology

Protective ImmunityAutoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunology +7

In Vivo Depletion of CD11c+ Dendritic Cells Abrogates Priming of CD8+ T Cells by Exogenous Cell-Associated Antigens

Steffen Jung, Derya Unutmaz, Phillip Wong, +10

Immunity

Vivo DepletionAutoimmune DiseaseExogenous Cell-associated AntigensImmunologyAntigen Processing +8

Determination of lymphocyte division by flow cytometry

A. Bruce Lyons, Christopher R. Parish

Journal of Immunological Methods

Flow CytometryImmunologyHematologyLymphatic SystemImmunophenotyping +5

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

Edith M. Janssen, Edward E. Lemmens, Tom Wolfe, +3

Nature

Autoimmune DiseaseAdaptive Immune SystemImmunologyAutoimmunityT Cell Immunity +8

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

Devon J. Shedlock, Hao Shen

Science

Cd4 HelpAdaptive Immune SystemNeurovirologyMedicinePathogenesis +12

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

Susan M. Kaech, Rafi Ahmed

Nature Immunology

Developmental BiologyAutoimmune DiseaseLymphocyte DevelopmentImmune Cell DevelopmentAdaptive Immune System +10

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

Joseph C. Sun, Michael J. Bevan

Science

InflammationCd4 HelpAutoimmune DiseaseAllergyAdaptive Immune System +13

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

Marianne J.B. van Stipdonk, Edward E. Lemmens, Stephen P. Schoenberger

Nature Immunology

Naïve CtlsSingle Brief PeriodSignal TransductionImmunologyPathology +8