Cancer · 1981 · 71 citations · 10 references
Cis-diamminedichloroplatinum is an effective neoplastic agent whose nephrotoxicity and ototoxicity are prominent side effects, yet ototoxicity studies have focused only on auditory function. This report details the first known case of vestibular toxicity following platinum therapy. The authors report a prospective vestibular testing program to assess this toxicity. Cancer 47:857–8589, 1981.
Cis-diamminedichloroplatinum has been proven to be an effective neoplastic agent. Nephrotoxicity and ototoxicity are two prominent side effects of this drug. Investigation of ototoxicity has been limited to auditory function. This report details the first known case of vestibular toxicity following platinum therapy. In addition, a prospective vestibular testing program is reported. Cancer 47:857–8589, 1981.
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Degenerative Changes in the Human Vestibular Sensory Epithelia
Ulf Rosenhall, Wallace Rubin · Acta Oto-Laryngologica · 1975 · 223 citations
Lawrence Helson, Elaine Okonkwo, Leslie Anton et al. · Clinical toxicology · 1978 · 147 citations