Concepedia

Reactive Oxygen Species‐Caspase‐3 Relationship in Mediating Blood–Brain Barrier Endothelial Cell Hyperpermeability Following Oxygen–Glucose Deprivation and Reoxygenation

Himakarnika Alluri, Hayden W. Stagg, Rickesha Wilson, Robert P. Clayton, Devendra A. Sawant, Madhavi Koneru, Madhava Beeram, Matthew L. Davis, Binu Tharakan

Microcirculation · 2013 · 38 citations · 21 references

DOI

Abstract

These results suggest that OGD-R-induced hyperpermeability is ROS and caspase-3 dependent and can be regulated by their inhibitors.

References

21

Actin stress fibers – assembly, dynamics and biological roles

Sari Tojkander, Gergana Gateva, Pekka Lappalainen · Journal of Cell Science · 2012 · 899 citations

, , +19

Cell-permeable Peptide Antioxidants Targeted to Inner Mitochondrial Membrane inhibit Mitochondrial Swelling, Oxidative Cell Death, and Reperfusion Injury

Kesheng Zhao, Guomin Zhao, Dunli Wu et al. · Journal of Biological Chemistry · 2004 · 775 citations · Full text

Three Distinct Mechanisms Generate Oxygen Free Radicals in Neurons and Contribute to Cell Death during Anoxia and Reoxygenation

Andrey Y. Abramov, Antonella Scorziello, Michael R. Duchen · Journal of Neuroscience · 2007 · 673 citations · Full text

Free radicals in cerebral ischemia.

Eugene S. Flamm, Harry B. Demopoulos, Myron L. Seligman et al. · Stroke · 1978 · 583 citations

, , +20

Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

Jean‐Ehrland Ricci, Roberta A. Gottlieb, Douglas R. Green · The Journal of Cell Biology · 2003 · 490 citations · Full text