Mutations within the S4–S5 Linker Alter Voltage Sensor Constraints in hERG K+ Channels

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +10

Crystal Structure of a Mammalian Voltage-Dependent <i>Shaker</i> Family K ⁺ Channel

Stephen B. Long, Ernest B. Campbell, Roderick MacKinnon · Science · 2005 · 2.1K citations

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

Stephen B. Long, Xiao Tao, Ernest B. Campbell et al. · Nature · 2007 · 1.4K citations

Membrane Structure, Membrane Biophysics, Biochemistry +11

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

Matthew C. Trudeau, Jeffrey W. Warmke, Barry Ganetzky et al. · Science · 1995 · 1.2K citations

Voltage Sensor of Kv1.2: Structural Basis of Electromechanical Coupling

Stephen B. Long, Ernest B. Campbell, Roderick MacKinnon · Science · 2005 · 997 citations