Concepedia

Value of<sup>18</sup>Fluorodeoxyglucose–Positron-Emission Tomography in Amyotrophic Lateral Sclerosis

Koen Van Laere, Annelies Vanhee, Jolien Verschueren, Liesbeth De Coster, An Driesen, Patrick Dupont, Wim Robberecht, Philip Van Damme

JAMA Neurology · 2014 · 143 citations · 29 references

DOIFull text

Open access

Abstract

18Fluorodeoxyglucose-positron-emission tomography is a useful early diagnostic and prognostic marker for ALS. Amyotrophic lateral sclerosis that is positive for C9orf72 is characterized by only mild cerebral metabolic differences that show no prognostic difference.

References

29

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

Alan E. Renton, Elisa Majounie, Adrian J. Waite et al. · Neuron · 2011 · 4.4K citations · Full text

, , +8

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

Elisa Majounie, Alan E. Renton, Kin Y. Mok et al. · The Lancet Neurology · 2012 · 1.2K citations · Full text

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EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) – revised report of an EFNS task force

European Journal of Neurology · 2011 · 1.1K citations

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study

Ilse Gijselinck, Tim Van Langenhove, Julie van der Zee et al. · The Lancet Neurology · 2011 · 625 citations

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Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations

Julie S. Snowden, Sara Rollinson, J. C. Thompson et al. · Brain · 2012 · 526 citations · Full text