Synthesis and biological evaluation of 2,8-disubstituted 9-benzyladenines: discovery of 8-mercaptoadenines as potent interferon-inducers

Tilorone Hydrochloride: An Orally Active Antiviral Agent

Russell F. Krueger, Gerald D. Mayer · Science · 1970 · 190 citations

Medicine, Pharmacology, Pharmacotherapy +8

Immunomodulating and antiviral activities of the imidazoquinoline S-28463

Mark A. Tomai, Sheila J. Gibson, Linda M. Imbertson et al. · Antiviral Research · 1995 · 130 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Induction of Interferon and Other Cytokines by Imiquimod and Its Hydroxylated Metabolite R-842 in Human Blood Cells <i>In Vitro</i>

Charles E. Weeks, Sheila J. Gibson · Journal of Interferon Research · 1994 · 110 citations

Medicine, Immunology, Pharmacology +8

Synthesis of Potential Anticancer Agents. XX. 2-Fluoropurines²

John A. Montgomery, Kathleen Hewson · Journal of the American Chemical Society · 1960 · 89 citations

Medicine, Medicinal Chemistry, Pharmacology +7

8-Substituted guanosine and 2'-deoxyguanosine derivatives as potential inducers of the differentiation of Friend erythroleukemia cells

Tai Shun Lin, Jia Chong Cheng, Kimiko Ishiguro et al. · Journal of Medicinal Chemistry · 1985 · 89 citations

Medicine, Medicinal Chemistry, Pharmacology +5