Obesity Research · 1993 · 220 citations · 123 references
EducationKinesiologyPhysiologyExercise PhysiologyExercise PrescriptionPhysical ActivityMetabolic Adaptation To ExerciseMetabolic Responses To ExerciseObesity ManagementPhysical FitnessWeight LossWeight ManagementExercise-induced Fatty Acid OxidationExercise-induced Weight LossImpaired Insulin SensitivityLow-intensity ExerciseMetabolic Complications ManagementMetabolic Rate RegulationSubstrate OxidationWeight Management Through Exercise
This paper reviews succinctly the evidence for a role of regular exercise in the prevention and the treatment of obesity and of its metabolic complications. Seventeen propositions relevant to an understanding of the topic are considered. The evidence suggests that regular exercise can be an important factor in the development of sustained negative energy balance conditions provided the volume of activity is high. This implies a program of low to moderate intensity exercise performed on an almost daily basis for at least one hour per session. To induce significant weight and fat losses and to treat overweight and obese patients, compliance to the program for several years becomes a necessity. Exercise increases lipid substrate oxidation and may favor carbohydrate intake for the same amount of energy intake. The acute effects of exercise on resting metabolic rate are well documented, but the long-term influences of exercise training seem to be small and are rapidly suppressed with the cessation of training. The obese benefits also from a regular exercise regimen in terms of improved insulin sensitivity, lipid and lipoprotein profile, and blood pressure, as well as reduced risk of death. Regular exercise, such as walking, is a healthy course of action for the overweight or the obese patients.
123
Physical Activity, All-Cause Mortality, and Longevity of College Alumni
Ralph S. Paffenbarger, Robert Hyde, Alvin L. Wing et al. · New England Journal of Medicine · 1986 · 2.8K citations
Education, Health Sciences, Aging +12
Physical Fitness and All-Cause Mortality
Steven N. Blair · JAMA · 1989 · 2.6K citations
The Response to Long-Term Overfeeding in Identical Twins
Claude Bouchard, Angelo Tremblay, Jean‐Pierre Després et al. · New England Journal of Medicine · 1990 · 1.3K citations · Full text