International Journal of Andrology · 1994 · 126 citations · 21 references
MedicineSurgeryContraceptionReproductive HealthReproductive MedicineContraceptive MethodsSafer Sex PracticesTesticular FunctionTesticular PhysiologyContraceptive Method ChoiceContraceptive Method EffectivenessHeat-based Male ContraceptionHeat-induced Testicular InjuryScrotal Temperature AssessmentTesticular Function AssessmentTesticular Temperature RegulationTesticular Thermoregulation
A preliminary assessment of the contraceptive efficacy of a daily mild increase (1-2 degrees C) in testicular temperature during waking hours is reported in nine couples using two techniques of non-surgical fixation of the testes close to the inguinal canal. With technique 1, immobilization was achieved by passing the penis and the empty scrotum through a hole made in close-fitting underwear; there was one pregnancy, from a man who stopped the heating after 7 weeks, for 42 cycles of exposure in three couples. With technique 2, immobilization was achieved by adding a ring of soft material surrounding the hole in the underwear; there was no pregnancy for 117 cycles of exposure in six couples. Reversibility and safety were assessed. These preliminary results suggest that a daily mild increase in testicular temperature could be a potential contraceptive method for men.
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Association of scrotal hyperthermia with impaired spermatogenesis in infertile men
Roger Mieusset, Louis Bujan, Charlotte Mondinat et al. · Fertility and Sterility · 1987 · 170 citations
Medicine, Urology, Infertility +15
THE EFFECT OF HYPERPYREXIA UPON SPERMATOZOA COUNTS IN MEN
John Macleod, Robert S. Hotchkiss · Endocrinology · 1941 · 146 citations
Effect of repeated increase of body temperature on human sperm cells.
Procopé Bj · PubMed · 1966 · 98 citations
Inhibiting effect of artificial cryptorchidism on spermatogenesis
Roger Mieusset, H. Grandjean, A Mansat et al. · Fertility and Sterility · 1985 · 88 citations
Life Sciences, Biomedical Sciences, Developmental Biology +12