Immobilization-free screening of aptamers assisted by graphene oxide

Jee-Woong Park, Rameshwar Tatavarty, Dae Woo Kim, Hee‐Tae Jung, Man Bock Gu

Chemical Communications · 2011 · 176 citations · 24 references

Concepts

Abstract

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

References

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