IVIg prevents the in vitro activation of T cells by neutralizing the T cell activators

HIGH-DOSE INTRAVENOUS GAMMAGLOBULIN FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA IN CHILDHOOD

Paul Imbach, V. D’Apuzzo, Andreas Hirt et al. · The Lancet · 1981 · 1.7K citations

Medicine, Hematology, Pediatrics +4

The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.

John M. Williams, D Deloria, J A Hansen et al. · The Journal of Immunology · 1985 · 188 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Expression patterns of Th1 and Th2 cytokine genes in childhood idiopathic thrombocytopenic purpura (ITP) at presentation and their modulation by intravenous immunoglobulin G (IVIg) treatment: their role in prognosis

Αthanasia Mouzaki, Ioannis Gianakopoulos, Vassiliki Vlaha et al. · Blood · 2002 · 144 citations · Full text

Life Sciences, Immunology, Pediatrics +13

Suppression of Cytokine-Dependent Human T-Cell Proliferation by Intravenous Immunoglobulin

David Amran, Harald Renz, Gideon Lack et al. · Clinical Immunology and Immunopathology · 1994 · 135 citations

Life Sciences, Cell Biology, Immunology +14

Alteration of T cell subsets and immunoglobulin synthesis in vitro during high dose gamma-globulin therapy in patients with idiopathic thrombocytopenic purpura.

T Tsubakio, Y. Kurata, Sayaka Katagiri et al. · PubMed · 1983 · 134 citations

Life Sciences, Hematology, Immunology +11