Journal of Clinical Psychopharmacology · 1991 · 137 citations · 15 references
MedicineNeurosciencePsychiatryNeuropsychiatryNeuropsychologyPsychopharmacologyAddictionDrug DependenceDrugs Of AbuseStimulant Use DisordersSubstance IntoxicationSubstance-related Neuropsychiatric DisordersBehavioral Manifestations Of IntoxicationMdma ToxicityMonoamine PharmacologyNeuropsychiatric EffectsNeuropsychiatric ManifestationsNeuropsychiatric SequelaeNeurotoxicity Of DrugsRecreational Drug Neurotoxicity
Two persons are described who demonstrated prolonged neuropsychiatric syndromes after the ingestion of large doses of (+-)-3,4-methylenedioxymethamphetamine (MDMA), a recreationally used amphetamine analog. These cases suggest that MDMA, known to be neurotoxic to serotonin neurons in several experimental animals, may also produce untoward effects in humans. In addition, they provide evidence that ingestion of large doses of MDMA can produce lasting adverse functional consequences in vulnerable persons.
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Elizabeth O’Hearn, Giuseppe Battaglia, EB De Souza et al. · Journal of Neuroscience · 1988 · 546 citations · Full text
Pharmacy, Neuroscience, Pharmacology +17
Giuseppe Battaglia, S.Y. Yeh, Elizabeth O’Hearn et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 459 citations
Medicine, Neuroscience, Pharmacology +16