Concepedia

Mutations in Innate Immune System NOD2/CARD 15 and TLR-4 (Thr399Ile) Genes Influence the Risk for Severe Acute Graft-versus-Host Disease in Patients Who Underwent an Allogeneic Transplantation

Ahmet Elmaağaclı, Michael Koldehoff, Heidrun Hindahl, Nina K. Steckel, Rudolf Trenschel, Rudolf Peceny, Hellmut Ottinger, Peter‐Michael Rath, Rudolf Stefan Ross, Michael Roggendorf,

Transplantation · 2006 · 131 citations · 26 references

Abstract

These results suggest that NOD2 mutations have influence on the occurrence of acute GVHD after transplantation.

References

26

Regression Models and Life-Tables

D. R. Cox · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1972 · 38.8K citations · Full text

Regression Models, Reliability Engineering, Conditional Likelihood +14

Nonparametric Estimation from Incomplete Observations

Edward L. Kaplan, Paul Meier · Journal of the American Statistical Association · 1958 · 38.7K citations

Engineering, Aging, Life Prediction +21

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Jean‐Pierre Hugot, Mathias Chamaillard, Habib Zouali et al. · Nature · 2001 · 5.6K citations

Inflammation, Autoimmune Disease, Immunology +6

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

Host Response, Toll-like Receptors, Signal Transduction +10

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Yasunori Ogura, Denise K. Bonen, Naohiro Inohara et al. · Nature · 2001 · 5K citations · Full text

Inflammation, Autoimmune Disease, Disease Mechanism +8