Idazoxan and 8-OH-DPAT Modify the Behavioral Effects Induced by Either NA, or 5-HT, or Dual NA/5-HT Reuptake Inhibition in the Rat Forced Swimming Test

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

Medicine, Neuroscience, Psychiatry +12

Behavioural despair in rats: A new model sensitive to antidepressant treatments

Roger D. Porsolt, Guy Anton, N. Blavet et al. · European Journal of Pharmacology · 1978 · 3.1K citations

Medicine, Behavioral Sciences, Neurobiology +13

Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants

Michael J. Detke, Michael R. Rickels, Irwin Lucki · Psychopharmacology · 1995 · 1.4K citations

Medicine, Neuroscience, Pharmacology +14

8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site

Derek N. Middlemiss, John R. Fozard · European Journal of Pharmacology · 1983 · 869 citations

Life Sciences, Neuroscience, Molecular Neuroscience +6

Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity

Roger D. Porsolt, Anne Bertin, N. Blavet et al. · European Journal of Pharmacology · 1979 · 577 citations

Medicine, Neuroscience, Pharmacology +14