Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import

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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

Andreas Bender, Kim J. Krishnan, Christopher M. Morris et al. · Nature Genetics · 2006 · 1.6K citations

Life Sciences, Genetics, Neuroscience +17

MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES

AnthonyW. Linnane, Takayuki Ozawa, S Marzuki et al. · The Lancet · 1989 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +12

Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation

Rebecca J. Carter, Lisa A. Lione, Trevor Humby et al. · Journal of Neuroscience · 1999 · 959 citations · Full text

Life Sciences, Neurology, Neuroscience +17