Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

Scott W. Lowe, Earlene M. Schmitt, Sallie W. Smith et al. · Nature · 1993 · 2.9K citations

Radiation-induced Apoptosis, Radiation Effect, Apoptosis +4

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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Multiple Advanced Cancers, Tumor Biology, Chromosome 10Q23.3 +10

Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.

Michael A. Davies, Dimpy Koul, Haninder Dhesi et al. · PubMed · 1999 · 275 citations

Mmac/pten Expression, Chemoprevention Strategy, Akt/pkb Activity +16

PTEN Induces Chemosensitivity in PTEN-mutated Prostate Cancer Cells by Suppression of Bcl-2 Expression

Haojie Huang, John C. Cheville, Yunqian Pan et al. · Journal of Biological Chemistry · 2001 · 183 citations · Full text