Effects of repeated MK-801 on ambulation in mice and in sensitization following methamphetamine

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Medicine, Neurology, Pharmacology +12

Blockade of “reverse tolerance” to cocaine and amphetamine by MK-801

Ralph Karler, L.I. Calder, Imtiaz A. Chaudhry et al. · Life Sciences · 1989 · 488 citations

Medicine, Pharmacology, Psychiatry +12

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

Maria Carlsson, Arvid Carlsson · Journal of Neural Transmission · 1989 · 426 citations

Life Sciences, Neuroscience, Pharmacology +16

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.

Wouter Koek, J H Woods, Gail Winger · Journal of Pharmacology and Experimental Therapeutics · 1988 · 307 citations

Life Sciences, Neuroscience, Pharmacology +16