Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain

The global distribution of clinical episodes of Plasmodium falciparum malaria

Robert W. Snow, Carlos A. Guerra, Abdisalan M. Noor et al. · Nature · 2005 · 2.7K citations · Full text

Veterinary Medicine, Health Sciences, Infectious Diseases +14

Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug Screening

Martin J. Smilkstein, Nongluk Sriwilaijaroen, Jane X. Kelly et al. · Antimicrobial Agents and Chemotherapy · 2004 · 1.2K citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +13

The structure of malaria pigment β-haematin

Silvina Pagola, Peter W. Stephens, D. Scott Bohle et al. · Nature · 2000 · 856 citations

Life Sciences, Biochemistry, Molecular Biology +5

Assessment and Continued Validation of the Malaria SYBR Green I-Based Fluorescence Assay for Use in Malaria Drug Screening

Jacob D. Johnson, Richard A. Dennull, Lucia Gerena et al. · Antimicrobial Agents and Chemotherapy · 2007 · 374 citations · Full text

Medicine, Pharmacology, Biopharmaceutics +14

Structure−Function Relationships in Aminoquinolines:  Effect of Amino and Chloro Groups on Quinoline−Hematin Complex Formation, Inhibition of β-Hematin Formation, and Antiplasmodial Activity

Timothy J. Egan, Roger Hunter, Catherine H. Kaschula et al. · Journal of Medicinal Chemistry · 1999 · 311 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10