Cu‐Catalyzed Enantioselective Conjugate Additions of Alkyl Zinc Reagents to Unsaturated<i>N</i>‐Acyloxazolidinones Promoted by a Chiral Triamide Phosphane

Abstract

A chiral triamide phosphane promotes highly efficient and enantioselective Cu-catalyzed conjugate additions of alkyl zinc compounds to unsaturated oxazolidinones (see scheme). The resulting β-alkyl chiral oxazolidinones are readily converted into synthetically useful carbonyl compounds not accessible by alternative catalytic methods.