Molecular Determinants of KCNQ1 Channel Block by a Benzodiazepine

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

D. Doyle, João H. Morais‐Cabral, Richard A. Pfuetzner et al. · Science · 1998 · 6.8K citations

Natural Sciences, Biochemistry, Biophysics +17

Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution

Yufeng Zhou, João H. Morais‐Cabral, Amelia Kaufman et al. · Nature · 2001 · 2.1K citations

Natural Sciences, Biochemistry, Chemistry +14

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Michael C. Sanguinetti, Mark Curran, Anruo Zou et al. · Nature · 1996 · 1.8K citations

Natural Sciences, Biochemistry, Molecular Biology +12

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Q. Wang, Mark Curran, Igor Splawski et al. · Nature Genetics · 1996 · 1.8K citations

Medicine, Genetics, Molecular Genetics +17

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

Medicine, Pharmacology, Anesthesia +16