Conformational analysis of substituted 1,2-oxathiane 2-oxides by ¹³C and ¹H nuclear magnetic resonance spectroscopy

Abstract

1 H and 13 C nmr results for 1,2-oxathiane 2-oxide and eight derivatives are reported. It is concluded that these molecules have a high preference for chair forms with axial S=O groups, even when a sterically bulky group such as phenyl is substituted in a syn-axial orientation to the exocyclic oxygen.