Simultaneous quantitation of etoposide and its catechol metabolite in human plasma using high-performance liquid chromatography with electrochemical detection

Etoposide and antimetabolite pharmacology in patients who develop secondary acute myeloid leukemia

M V Relling, Yuri Yanishevski, J.F. Nemec et al. · Leukemia · 1998 · 188 citations

Medicine, Oncology, Pharmacology +14

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.

Mary V. Relling, J.F. Nemec, Erin G. Schuetz et al. · Molecular Pharmacology · 1994 · 180 citations

Medicine, Pharmacology, Biochemical Pharmacology +16

Analysis of the anticancer drugs VP 16-213 and VM 26 and their metabolites by high-performance liquid chromatography

Robert J. Strife, Ian Jardine, Michael Colvin · Journal of Chromatography B Biomedical Sciences and Applications · 1980 · 90 citations

Pharmacy, Oncology, Pharmacology +16

VP-16-213 (etoposide): The mandrake root from Issyk-Kul

Nicholas J. Vogelzang, Derek Raghavan, B. J. Kennedy · The American Journal of Medicine · 1982 · 78 citations

Life Sciences, Molecular Biology, Plant Anatomy +1

Peroxidase-catalyzed metabolism of etoposide (VP-16-213) and covalent binding of reactive intermediates to cellular macromolecules.

Nissim Haim, J.F. Nemec, Birandra K. Sinha · PubMed · 1987 · 75 citations

Life Sciences, Biochemistry, Pharmacology +13