Physics in Medicine and Biology · 2008 · 23 citations · 28 references
EngineeringMeasurementX-ray Imaging SystemsX-ray FluorescenceX-ray ImagingRadiographyCalibrationNoisePhoton-counting Computed TomographyInstrumentationNuclear MedicineAdditive Instrumentation NoiseRadiologyHealth SciencesRadiation DetectionMedical ImagingInstrumentation NoiseComputer EngineeringSynchrotron RadiationRadiographic ImagingDosimetryBiomedical ImagingClinical PracticeX-ray Optic
The performance of high-sensitivity x-ray imagers may be limited by additive instrumentation noise rather than by quantum noise when operated at the low exposure rates used in fluoroscopic procedures. The equipment-invasive instrumentation noise measures (in terms of electrons) are generally difficult to make and are potentially not as helpful in clinical practice as would be a direct radiological representation of such noise that may be determined in the field. In this work, we define a clinically relevant representation for instrumentation noise in terms of noise-equivalent detector entrance exposure, termed the instrumentation noise-equivalent exposure (INEE), which can be determined through experimental measurements of noise-variance or signal-to-noise ratio (SNR). The INEE was measured for various detectors, thus demonstrating its usefulness in terms of providing information about the effective operating range of the various detectors. A simulation study is presented to demonstrate the robustness of this metric against post-processing, and its dependence on inherent detector blur. These studies suggest that the INEE may be a practical gauge to determine and compare the range of quantum-limited performance for clinical x-ray detectors of different design, with the implication that detector performance at exposures below the INEE will be instrumentation-noise limited rather than quantum-noise limited.
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Radiology · 2001 · 719 citations
Arthur E. Burgess · Journal of the Optical Society of America A · 1999 · 252 citations
CCD noise removal in digital images
H. Faraji, W. James MacLean · IEEE Transactions on Image Processing · 2006 · 150 citations