The orphan GPCR, GPR88, modulates function of the striatal dopamine system: A possible therapeutic target for psychiatric disorders?

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

Philip Seeman, M. Chau-Wong, J. L. Tedesco et al. · Proceedings of the National Academy of Sciences · 1975 · 702 citations · Full text

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Modulation of the Startle Response and Startle Laterality in Relatives of Schizophrenic Patients and in Subjects With Schizotypal Personality Disorder: Evidence of Inhibitory Deficits

Kristin S. Cadenhead, Neal R. Swerdlow, Kathleen M. Shafer et al. · American Journal of Psychiatry · 2000 · 355 citations

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Dopamine supersensitivity correlates with D2 ^High states, implying many paths to psychosis

Philip Seeman, David Weinshenker, Rémi Quirion et al. · Proceedings of the National Academy of Sciences · 2005 · 351 citations

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Diverse Psychotomimetics Act Through a Common Signaling Pathway

Per Svenningsson, Eleni T. Tzavara, Robert Carruthers et al. · Science · 2003 · 312 citations

Life Sciences, Neuroscience, Pharmacology +17

Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation

Wen Guo, Lei Shi, Marta Filizola et al. · Proceedings of the National Academy of Sciences · 2005 · 288 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17