Concepedia

Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines

Katarina Hostanska, J. Reichling, Silvia Bommer, Michel Weber, Reinhard Saller

European Journal of Pharmaceutics and Biopharmaceutics · 2003 · 144 citations · 49 references

DOI

Concepts

References

49

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

I. Vermes, C. Haanen, H M Steffens-Nakken et al. · Journal of Immunological Methods · 1995 · 5.3K citations · Full text

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Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

Elizabeth A. Slee, Mary T. Harte, Ruth M. Kluck et al. · The Journal of Cell Biology · 1999 · 1.9K citations · Full text

Distinct Caspase Cascades Are Initiated in Receptor-mediated and Chemical-induced Apoptosis

Xiaoming Sun, Marion MacFarlane, Jianguo Zhuang et al. · Journal of Biological Chemistry · 1999 · 823 citations · Full text

A Combined Assay of Cell Viability and in Vitro Cytotoxicity with a Highly Water-Soluble Tetrazolium Salt, Neutral Red and Crystal Violet.

Munetaka Ishiyama, Hideyuki Tominaga, Masanobu Shiga et al. · Biological and Pharmaceutical Bulletin · 1996 · 722 citations · Full text

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Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms

Chafké Ahmed Belmokhtar, Josette Hillion, E. Segal · Oncogene · 2001 · 474 citations

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