Concepedia

TISSUE TRANSGLUTAMINASE: A MEDIATOR AND PREDICTOR OF CHRONIC ALLOGRAFT NEPHROPATHY?

Timothy S. Johnson, Hamdy Abo-Zenah, Nicholas J. Skill, Samantha Bex, G. Wild, Colin B. Brown, Martin Griffin, A. Meguid El Nahas

Transplantation · 2004 · 19 citations · 19 references

DOI

Abstract

tTg and epsilon-(gamma-glutamyl) lysine crosslink correlated with the initiation and progression of scarring on sequential biopsies from renal-allograft recipients who experienced CAN. Elevated tTg may offer an early predictor of the development of CAN, whereas tTg manipulation may be an attractive therapeutic target.

References

19

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Lorraine C. Racusen, Kim Solez, Robert B. Colvin et al. · Kidney International · 1999 · 3K citations

International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology

Kim Solez, Roy A. Axelsen, Hallgrímur Benediktsson et al. · Kidney International · 1993 · 1.5K citations

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Latent Transforming Growth Factor-β Binding Protein Domains Involved in Activation and Transglutaminase-dependent Cross-Linking of Latent Transforming Growth Factor-β

Irene Nunes, Pierre‐Emmanuel Gleizes, Christine N. Metz et al. · The Journal of Cell Biology · 1997 · 392 citations · Full text

BOTH ALLOANTIGEN-DEPENDENT AND -INDEPENDENT FACTORS INFLUENCE CHRONIC ALLOGRAFT REJECTION

Stefan G. Tullius, Nicholas L. Tilney · Transplantation · 1995 · 370 citations

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BOTH ALLOANTIGEN-DEPENDENT AND -INDEPENDENT FACTORS INFLUENCE CHRONIC ALLOGRAFT REJECTION

Stefan G. Tullius, Nicholas L. Tilney · Transplantation · 1995 · 343 citations

, , +16