Concepedia

Immunostimulatory sequence DNA linked to the Amb a 1 allergen promotes TH1 cytokine expression while downregulating TH2 cytokine expression in PBMCs from human patients with ragweed allergy

Jason D. Marshall, Simin Abtahi, Joseph J. Eiden, Stephen Tuck, Robert Milley, Fiona Haycock, Michael J. Reid, Anne Kagey‐Sobotka, Peter S. Creticos, Lawrence M. Lichtenstein,

Journal of Allergy and Clinical Immunology · 2001 · 130 citations · 31 references

DOI

Concepts

References

31

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

, , +17

Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants

Mark Roman, Elena Martín‐Orozco, Justin S. Goodman et al. · Nature Medicine · 1997 · 916 citations

, , +14

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

Gunther Hartmann, George J. Weiner, A M Krieg · Proceedings of the National Academy of Sciences · 1999 · 624 citations

, , +17

Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells

Gunther Hartmann, Arthur Μ. Krieg · The Journal of Immunology · 2000 · 601 citations

, , +17

Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo

Gunther Hartmann, Risini D. Weeratna, Zuhair K. Ballas et al. · The Journal of Immunology · 2000 · 586 citations

, , +14