Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells - Concepedia

Concepedia

Publication | Open Access

Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells

DOI Full Paper Access

125

Citations

24

References

2013

Year

Esther Bertrán, Eva Crosas‐Molist, Patricia Sancho, Laia Caja, Judit López‐Luque, Estanis Navarro, Gustavo Egea, Raquel Lastra, Teresa Serrano, Emilio Ramos,

Abstract

A crosstalk exists among the TGF-β and CXCR4 pathways in liver tumors, reflecting a novel molecular mechanism that explains the protumorigenic effects of TGF-β and opens new perspectives for tumor therapy.

References

	Year	Citations

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