Sequence analysis of the <i>PRKAR1A</i> gene in sporadic somatotroph and other pituitary tumours

Abstract

No mutations were found in any of the exons sequenced. Relative mRNA expression was not decreased in any of the sporadic pituitary tumour samples. The present data thus do not suggest a major role for the PRKAR1A tumour suppressor gene in sporadic GH-secreting or other pituitary tumours.