Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways

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Ahmedin Jemal, Rebecca L. Siegel, Jiaquan Xu et al. · CA A Cancer Journal for Clinicians · 2010 · 12.6K citations · Full text

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The Pathophysiology of Mitochondrial Cell Death

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Life Sciences, Cell Biology, Molecular Biology +17

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Yasuyuki Suzuki, Yuzuru Imai, Hiroshi Nakayama et al. · Molecular Cell · 2001 · 1.1K citations · Full text

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Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice

Huanjie Yang, Di Chen, Qiuzhi Cindy Cui et al. · Cancer Research · 2006 · 585 citations

Medicine, Oncology, Pharmacology +13

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

Tao Zhang, Adel Hamza, Xianhua Cao et al. · Molecular Cancer Therapeutics · 2008 · 368 citations · Full text

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