Concepedia

Loss of P2Y2 Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer's Disease

Deepa Ajit, Lucas T. Woods, Jean M. Camden, Christina N. Thebeau, Farid G. El-Sayed, Glen W. Greeson, Laurie Erb, Michael J. Petris, Douglas C. Miller, Grace Y. Sun,

Molecular Neurobiology · 2013 · 56 citations · 65 references

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65

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba et al. · Nature · 2006 · 3.5K citations

, , +10

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

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Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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Soluble pool of A? amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

Catriona McLean, Robert A. Cherny, Fiona Fraser et al. · Annals of Neurology · 1999 · 1.8K citations

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