HIV-1 biological phenotype and the development of zidovudine resistance in relation to disease progression in asymptomatic individuals during treatment - Concepedia

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HIV-1 biological phenotype and the development of zidovudine resistance in relation to disease progression in asymptomatic individuals during treatment

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References

1992

Year

Charles A.B. Boucher, J Lange, Frank Miedema, Gerrit Jan Weverling, Maarten Koot, Jan W. Mulder, Jaap Goudsmit, Paul Kellam, Brendan Larder, Matthijs Tersmette

Abstract

Conversion to the SI phenotype cannot be prevented by zidovudine treatment. The presence or appearance of an SI virus heralded disease progression in zidovudine-treated individuals. Further research is required to investigate the relationship between virus phenotype and development of zidovudine resistance.