Investigation on uranyl interaction with bioactive ligands. Synthesis and structural studies of the uranyl complexes with glycine and <i>N</i>-(2-mercaptopropionyl)glycine

Abstract

Summary Three new uranium(VI) compounds have been prepared with glycine (Hgly), N -(2-mercaptopropionyl)glycine (Hmpg) and 2,2′-dithiobis( N -propionylglycine) (tpg). The crystal structure of [UO 2 (Hgly) 2 Cl 2 ] has been solved, revealing the uranium atom to be seven-co-ordinated. The two zwitterionic glycines are coordinated to uranium atom by the carboxylate groups, one in a monodentate and the other in a bidentate mode. Solid state studies and low temperature 1 H, 13 C, 2D COSY and HMQC solution NMR spectra of the [UO 2 (mpg)(CH 3 COO)], show that mpg coordinates uranium atom by the carboxylate group.