Ultrafine Hydrogel Nanoparticles: Synthetic Approach and Therapeutic Application in Living Cells

Abstract

Licensed to kill: A method for obtaining ultrafine hydrophilic polyacrylamide-based nanoparticles that encapsulate meta-tetra(hydroxyphenyl)chlorin (mTHPC) has been developed. Rat C6 glioma cells exposed to infrared light were killed (red) in the presence of the mTHPC-encapsulating nanoparticles while the cells without exposure to light were still alive (green). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z603927_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.