Concepedia

Interaction of Human Mesenchymal Stem Cells With Disc Cells

Catherine Le Visage, Seok Woo Kim, Kei Tateno, Ann N. Sieber, John P. Kostuik, Kam W. Leong

Spine · 2006 · 97 citations · 12 references

DOI

Abstract

Addition of MSCs to AF cells resulted in an up-regulation of the proteoglycans synthesis. This study provides the rationale for further investigation of the potential of MSC therapy in treating intervertebral disc degeneration.

References

12

Chondrogenic Differentiation of Cultured Human Mesenchymal Stem Cells from Marrow

Alastair M. Mackay, Stephen C. Beck, Mary Murphy et al. · Tissue Engineering · 1998 · 1.3K citations · Full text

Stimulation of Mature Canine Intervertebral Disc by Growth Factors

J. PAUL THOMPSON, THEODORE R. OEGEMA, DAVIDS BRADFORD · Spine · 1991 · 411 citations

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Notochordal Cells Interact with Nucleus Pulposus Cells: Regulation of Proteoglycan Synthesis

Dean J. Aguiar, Sandra L. Johnson, Theodore R. Oegema · Experimental Cell Research · 1999 · 321 citations

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Initial characterization of the metabolism of intervertebral disc cells encapsulated in microspheres

Brian A. Maldonado, Theodore R. Oegema · Journal of Orthopaedic Research® · 1992 · 213 citations

Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: An <i>in vitro</i> and <i>in vivo</i> experimental study

Masahiko Okuma, Joji Mochida, Kazuhiro Nishimura et al. · Journal of Orthopaedic Research® · 2000 · 207 citations

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