Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc

Daisuke Sakai, Yoshihiko Nakamura, Tomoko Nakai, +12

Nature Communications

Transplantation of mesenchymal stem cells embedded in Atelocollagen® gel to the intervertebral disc: a potential therapeutic model for disc degeneration

Daisuke Sakai, Joji Mochida, Y. Yamamoto, +6

Biomaterials

Tissue EngineeringCell TherapyEngineeringIntervertebral DiscBiomedical Engineering +14

Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc

Daisuke Sakai, Joji Mochida, Toru Iwashina, +6

Biomaterials

Regenerative MedicineTissue EngineeringMesenchymal Stem CellsDevelopmental BiologyMedicine +9

Differentiation of Mesenchymal Stem Cells Transplanted to a Rabbit Degenerative Disc Model

Daisuke Sakai, Joji Mochida, Toru Iwashina, +4

Spine

Transplantation of mesenchymal stem cells in a canine disc degeneration model

Akihiko Hiyama, Joji Mochida, Toru Iwashina, +5

Journal of Orthopaedic Research®

Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: An <i>in vitro</i> and <i>in vivo</i> experimental study

Masahiko Okuma, Joji Mochida, Kazuhiro Nishimura, +2

Journal of Orthopaedic Research®

Tissue EngineeringEngineeringIntervertebral DiscPathologyCell Culture +18

Nucleus Pulposus Allograft Retards Intervertebral Disc Degeneration

Takeshi Nomura, Joji Mochida, Masahiko Okuma, +2

Clinical Orthopaedics and Related Research

A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat

Cynthia R. Lee, Daisuke Sakai, Tomoko Nakai, +4

European Spine Journal

MechanobiologyDegenerative SpineEngineeringIntervertebral DiscPhenotypic Comparison +9

Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model

Kenji Serigano, Daisuke Sakai, Akihiko Hiyama, +3

Journal of Orthopaedic Research®

Tissue EngineeringCell TherapyEngineeringBiomedical EngineeringStem Cell Biology +16

Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration

Joost Rutges, Laura B. Creemers, Wouter J.A. Dhert, +5

Osteoarthritis and Cartilage

MechanobiologyRegenerative MedicineIntervertebral DiscGeneticsHuman Tissue +9