Insulin receptor substrate 1 modulates the transcriptional activity and the stability of androgen receptor in breast cancer cells

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

Vito J. Palombella, Oliver J. Rando, Alfred L. Goldberg et al. · Cell · 1994 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +11

Phosphorylation‐dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

Hui-Kuan Lin, Liang Wang, Saleh Altuwaijri et al. · The EMBO Journal · 2002 · 452 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2

OwenW. J. Prall, Boris Šarčević, Elizabeth A. Musgrove et al. · Journal of Biological Chemistry · 1997 · 447 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17

Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-I.

Susan M. Aronica, Benita S. Katzenellenbogen · Molecular Endocrinology · 1993 · 436 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter

Kitty B.J.M. Cleutjens, Conny C. Ehren-van Eekelen, Hetty A. G. M. van der Korput et al. · Journal of Biological Chemistry · 1996 · 415 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +16